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目的比较兰索拉唑、雷尼替丁治疗消化性溃疡出血的疗效和安全性。方法将96例患者随机分为兰索拉唑组(治疗组)和雷尼替丁组(对照组),分别给予兰索拉唑及雷尼替丁治疗。结果两组显效率分别为86.00%与52.17%,二者比较差异有统计学意义(P<0.01)。结论兰索拉唑治疗消化性溃疡出血疗效明显优于雷尼替丁,且安全、迅速、有效。
Objective To compare the efficacy and safety of lansoprazole and ranitidine in the treatment of peptic ulcer bleeding. Methods 96 patients were randomly divided into lansoprazole group (treatment group) and ranitidine group (control group), respectively, lansoprazole and ranitidine treatment. Results The effective rates of the two groups were 86.00% and 52.17%, respectively, with significant difference between the two groups (P <0.01). Conclusions Lansoprazole treatment of peptic ulcer bleeding was significantly better than ranitidine, and safe, rapid and effective.