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昆明种小鼠３２只，其中老年鼠２４只（１８～２４个月）分成Ａ、Ｂ两组；青年鼠（３～４个月）８只为Ｃ组。Ａ组小鼠饮用左归饮加减的常规汤剂７５天后，各组小鼠均取血１ｍｌ，以国产ＤＪＨ型单环血栓仪进行体外血栓监测。结果：Ａ、Ｂ两组体外血栓的长度和重量明显高于青年组（Ｐ＜０．０１），Ａ组低于Ｂ组（Ｐ＜０．０５）。实验结果表明，小鼠的体外血栓随增龄而增长和增重，证明左归饮加减而成的汤剂有明显改善血液循环的作用。
There were 32 Kunming mice, of which 24 (18-24 months) old mice were divided into A and B groups; 8 young rats (3 to 4 months) were in group C. In group A, mice were treated with Zuogui Yin addition and subtraction of conventional decoction. After 75 days, 1 ml of blood was collected from each group. In vitro thrombus monitoring was performed with a domestic DJH single-loop thrombus apparatus. Results: The length and weight of extracorporeal thrombus in group A and B were significantly higher than that in young group (P<0.01), and in group A was lower than that in group B (P<0.05). The experimental results show that the in vitro thrombus of mice increases and increases with age, which proves that the decoction of Zuo Gui Yin has obvious effect on improving blood circulation.