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本文收集1986年以来在B超引导下经皮细针吸取细胞学诊断肝脏肿物并具有组织学针吸活检的102例进行对比研究。结果证明:细胞学检查敏感性及特异性分别为93.1％及100％;而组织学活检分别为87.1％及100％。本检查对B超发现肝占位性病变而α-FP检查阴性者具有特殊意义。由于多为α-FP阴性病例,故以分化好的肝癌、肝母细胞瘤、转移癌及肉瘤等占有较高比例。这类病例单凭细胞学诊断存在一定困难、而组织学检查则常能弥补其不足。唯后者取材失败率较高,细胞学诊断效果较好。如能二者结合互补后,阳性率可近于100％。
In this article, we collected 102 patients who underwent ultrasound-guided needle-guided cytological diagnosis of liver tumors and had histological needle biopsy under the guidance of B-ultrasound. The results showed that the sensitivity and specificity of cytology were 93.1% and 100%, respectively; and the histological biopsies were 87.1% and 100%, respectively. This test has special significance for the detection of liver occupying lesions by B-mode ultrasonography but negative for α-FP. Because they are mostly negative for α-FP, they have a higher proportion of differentiated liver cancer, hepatoblastoma, metastatic cancer, and sarcoma. There are certain difficulties in the diagnosis of such cases based on cytology alone, and histological examination can often make up for their deficiencies. Only the latter had a higher failure rate and a better cytological diagnosis. If the two can be combined and complementary, the positive rate can be close to 100%.