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本文报告应用氟胞嘧啶治疗24例真菌感染取得良好结果。21例系单独使用氟胞嘧啶,3例则并用两性霉素B。致病菌有新型隐球菌、白色串珠苗,热带串珠菌及球拟酵母菌(Torulopsis glabrata)。 24例中3例肺部隐球菌感染、2例白色串珠菌眼内感染以及8例由白色串珠菌或球拟酵母菌引起的尿路感染疗效最佳,结果痊愈。1例隐球菌引起的肺及脊椎感染也获得良好的临床效果。4例有其他严重疾病并发播散性串珠菌病的患者2例获得痊愈,作者综合应用两性霉素B和氟胞嘧啶治疗了3例重笃患者,1例隐球菌性脑膜炎合并有椎管感染,
This paper reports the use of flucytosine treatment of 24 cases of fungal infections achieved good results. 21 cases were treated with flucytosine alone, 3 cases with amphotericin B. Pathogens are Cryptococcus neoformans, white string beads, strains of Candida and Torulopsis glabrata. In 24 cases, 3 cases of cryptococcosis of the lung, 2 cases of streptococcus infection, and 8 cases of urinary tract infections caused by Leuconostoccus or Globular yeast were the best, and the results were cured. One case of cryptococcal lung and spine infection also received good clinical results. 4 cases of other serious diseases associated with streptozotocosis patients were cured in 2 cases, the authors combined amphotericin B and flucytosine in the treatment of 3 cases of patients, 1 case of cryptococcal meningitis with spinal canal infection,