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本实验用肠炎杆菌攻击正常小白鼠，肠炎杆菌菌液浓度为１０８个／ｍｌ，灌喂０．２ｍｌ，造成肠炎杆菌在肠道内大量定植后，分别用中药人参合剂及复方新诺明（ＣＯ－ＳＭＺ）治疗，连续６天后，观察对比两种药物对受攻击小鼠的治病效果。检测小鼠粪便中的四种菌群成员，肠炎杆菌、肠杆菌、双歧杆菌和乳杆菌。结果表明：中药人参合剂治疗组肠炎杆菌显著下降，与ＣＯ－ＳＭＺ组相似（Ｐ＞０．０５），但双歧杆菌与乳杆菌显著升高，与复方新诺明组相比有显著性差异（Ｐ＜０．０５）。我们认为中药人参合剂治疗肠道感染的主要机制是中药人参合剂扶植正常菌群生长，提高小鼠的定植抗力的作用。
In this experiment, the normal mice were challenged with enterobacteriaceae. The concentration of enterointestinal bacteria was 108/ml and 0.2 ml was fed. This resulted in a large number of colonic colonization of enterointestinal tracts and the use of traditional Chinese medicine ginseng mixture and compound sulfamethoxazole (CO-). After SMZ) treatment for 6 consecutive days, the therapeutic effects of the two drugs on the challenged mice were observed and compared. Four members of the bacterial flora in mouse feces were tested for Enterobacteriaceae, Enterobacteriaceae, Bifidobacteria and Lactobacillus. The results showed that the enterococci of the traditional Chinese medicine ginseng mixture treatment group was significantly decreased, similar to the CO-SMZ group (P>0.05), but the Bifidobacteria and Lactobacillus were significantly increased, and there was a significant difference compared with the compound sulfamethoxazole group. (P<0.05). We believe that the main mechanism of traditional Chinese medicine ginseng mixture in the treatment of intestinal infection is the role of traditional Chinese medicine ginseng mixture in fostering the growth of normal flora and improving the colonization resistance of mice.