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本研究建立了幽门螺杆菌的近缘苗猪胃螺杆菌的SPF级Balb/c小鼠模型,发现细菌可在其中长期定植并引起与人类Hp相关胃炎相似的组织学改变,提示该模型可用于幽门螺杆菌的研究。
In this study, we established a model of Balb / c mouse model of Helicobacter pylori infection with Staphylococcus aureus and found that the bacteria could colonize for a long time and cause histological changes similar to human Hp-related gastritis, suggesting that the model can be used in pylorus Helicobacter research.