论文部分内容阅读
目的探讨血液灌流联合血液透析在急性肾衰竭中的应用效果。方法选取2013年1月—2015年1月南昌大学第二附属医院收治的急性肾衰竭患者60例,根据治疗方法不同将患者分为试验组与对照组,各30例。试验组采取血液灌流联合血液透析治疗,对照组采取单纯血液透析治疗,比较两组患者治疗前后血肌酐、血尿素氮水平及肾功能恢复时间、住院时间。结果治疗前两组患者血肌酐、血尿素氮水平比较,差异无统计学意义(P>0.05);治疗后试验组血肌酐、血尿素氮水平低于对照组,差异有统计学意义(P<0.05);治疗后试验组血肌酐、血尿素氮水平均在参考范围,对照组血肌酐、血尿素氮水平高于参考范围上限。试验组肾功能恢复时间、住院时间短于对照组,差异有统计学意义(P<0.05)。结论血液灌流联合血液透析治疗急性肾衰竭的临床效果明显,可有效改善患者肾功能指标,缩短治疗时间。
Objective To investigate the effect of hemoperfusion combined with hemodialysis in acute renal failure. Methods Sixty patients with acute renal failure admitted to the Second Affiliated Hospital of Nanchang University from January 2013 to January 2015 were selected. The patients were divided into experimental group and control group with 30 cases in each group according to different treatment methods. The experimental group was treated with hemoperfusion combined with hemodialysis. The control group was treated with hemodialysis alone. The serum creatinine, blood urea nitrogen level, renal function recovery time and hospital stay before and after treatment were compared between the two groups. Results There was no significant difference in serum creatinine and blood urea nitrogen between the two groups before treatment (P> 0.05). After treatment, serum creatinine and blood urea nitrogen in the experimental group were lower than those in the control group (P < 0.05). After treatment, the serum creatinine and blood urea nitrogen in the experimental group were within the reference range. The serum creatinine and blood urea nitrogen levels in the control group were higher than the upper limit of the reference range. The renal function recovery time and hospitalization time in the experimental group were shorter than those in the control group, with significant difference (P <0.05). Conclusion Hemoperfusion combined with hemodialysis treatment of acute renal failure has obvious clinical effect, which can effectively improve renal function indexes and shorten the treatment time.