人参皂苷为人参主要的药理活性组成部分,通过水解二醇系人参皂苷的糖苷配基是制备稀有人参皂的常用方法。酶法转化因其底物高度专一、条件温和、副产物少等潜在优势而被作为结构修饰和生理研究的主要技术手段。本文主要对糖苷酶转化人参皂苷研究进展进行了综述,为其工业化生产高活性皂苷提供理论依据。 Ginsenosides are the major pharmacologically active components of ginseng. The common method for preparing rare ginseng soaps is to hydrolyze the aglycone of the ginsenosides of diols. Enzymatic transformation is regarded as the main technical means of structural modification and physiological research due to its potential of being highly substrate-specific, mild in condition, with few by-products. This review summarizes the research progress of glycosidase transformation of ginsenosides and provides a theoretical basis for its industrial production of highly active saponins.