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作者设计与体内情况相似的体外膀胱模型,使细菌能在类似真正膀胱所具有的稀释及周期性排尿的条件下生长,并按治疗方案受到不断变化的药物浓度的作用。选择6种治疗泌尿道感染有代表性的抗菌素:
The authors designed an in vitro model of the bladder that resembles the in vivo condition, allowing the bacteria to grow on conditions similar to the dilution and periodic urination of a true bladder, subject to ever-changing drug concentrations per treatment regimen. Choose 6 types of antibiotics that are typical for urinary tract infections: