一、肿瘤的免疫性早在19世纪末20世纪初期,已有人注意到肿瘤免疫问题,但由于当时受微生物免疫的影响,对免疫的作用仅属限于纯培养细菌抗原的体液免疫方面。而且对同种免疫的存在和相关抗原尚不了解,故多年来的研究进展不大。在1929—1932年Haushka Poley对肿瘤免疫作了一个悲观的总结,认为肿瘤没有免疫性,以否虽有继续进行研究,但没有突破性进展。 I. Immunity of tumors As early as the end of the 19th century and the early 20th century, the problem of tumor immunity has been noticed. However, due to the influence of microbial immunity at that time, the effect on immunity was limited to the humoral immunity of purely cultured bacterial antigens. Moreover, the existence of alloimmunization and related antigens are still unknown, so little progress has been made over the years. In 1929-1932, Hasushka Poley made a pessimistic summary of tumor immunity. He believed that tumors were not immune. Whether or not they continued to conduct research, there was no breakthrough.