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文献中关于特发性水肿病人在立位时是否出现血浆肾素活性(PRA)和醛固酮(PA)过度反应,从而导致钠、水潴留,尚有不同意见。以前作者曾发现,正常人(即使在卧位)醛固酮分泌是阵发性的,高峰在早晨睡醒前后。本文研究目的是确定特发性水肿病人在卧位时,醛固酮分泌的昼夜节律是否改变,并研究醛固酮阵发分泌与及时血浆皮质醇和肾素活性之间的关系。4名患特发性水肿已3～20年的女病人选为研究对象,在研究期间都有轻至中度水
In the literature, Idiopathic edema in the standing position of plasma renin activity (PRA) and aldosterone (PA) over-reaction, resulting in sodium and water retention, there are different opinions. Previous authors have found that normal (even in lying position) aldosterone secretion is paroxysmal, peak before and after waking up in the morning. The aim of this study was to determine if the circadian rhythm of aldosterone secretion changes in patients with idiopathic edema and to study the relationship between aldosterone secretion and timely plasma cortisol and renin activity. Four female patients with idiopathic edema who had been treated for 3 to 20 years were selected as subjects, with light to moderate water during the study period