过去十年,在血吸虫免疫学范畴里,大量研究工作正朝着长远的目标——生产一种有效的抗血吸虫疫苗努力。这种疫苗的研制似乎取决于对血吸虫表面生物学的进一步了解。现有的研究结果表明,血吸虫童虫的表面抗原对宿主的免疫攻击起着靶子的作用。这些靶抗原随着血吸虫的发育而瞒着宿主隐藏下来,这样就逃避了宿主的免疫。 In the past decade, a large number of research efforts in the area of ​​schistosome immunology are moving toward the long-term goal of producing an effective anti-schistosome vaccine. The development of this vaccine seems to depend on a better understanding of schistosome surface biology. The existing research results show that the surface antigen of Schistosoma japonicum can play a target role in the host immune attack. With the development of schistosomes, these target antigens are hidden from the host and escape the host’s immunity.