POEMS综合征为侵犯多系统器官之症状群。主要临床特点为:多发性神经病变(Polyneuropathy)、内脏器官肿大(Organomegaly)、内分泌腺病变(Endocrinopathy)、M—蛋白及皮肤病变(Skinchanges)。各取每类病变之英文字首连缀而成其名。有的学者将各个系统所表现的主要临床现象归纳如下:(-)多发性神经病变:以周围神经病变出现率最多(100%),次为脑脊液内蛋白增加(94%)及视乳头水肿 POEMS syndrome is a syndrome that affects multiple system organs. The main clinical features are: polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes. Take the name of each type of lesion in the English prefix. Some scholars summarize the main clinical manifestations of each system as follows: (-) Polyneuropathy: the highest incidence of peripheral neuropathy (100%), followed by an increase of cerebrospinal fluid protein (94%) and papilledema