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目的:分析美沙酮维持治疗在预防艾滋病(HIV)中的应用。方法:抽取2015年5月-2016年3月期间就诊的美沙酮维持治疗的426例受治者作为研究对象,分析HIV人口分布情况以及治疗后的转阴、行为改善等情况。结果:性别方面,男性203例(47.65%),女性223例(52.35%),对比差异显著(X~2=2.697,P=0.043);长时间接受美沙酮维持治疗患者例数由治疗前125例(29.34%)增加至治疗后341例(80.05%),对比差异显著(P<0.05);具有生活信心由治疗前136例(31.92%)增加至治疗后339例(79.58%),对比差异显著(P<0.05);治疗后吗啡阳性率89.20%(380/426),治疗前91.55%(390/426),对比差异不显著(X~2=0.974,P=0.55)。结论:美沙酮维持治疗在HIV预防过程中,可明显改善患者的行为,使其主动参与治疗,而且有利于改善尿检结果,具有较高应用价值。
Objective: To analyze the application of methadone maintenance treatment in the prevention of AIDS. METHODS: A total of 426 subjects treated with methadone maintenance treatment from May 2015 to March 2016 were selected as study subjects to analyze the distribution of HIV population and the negative conversion and behavioral improvement after treatment. Results: In gender, there were 203 males (47.65%) and 223 females (52.35%) with significant difference (X ~ 2 = 2.697, P = 0.043). The number of patients receiving methadone maintenance therapy for a long time was (29.34%) increased to 341 cases (80.05%) after treatment, the difference was significant (P <0.05); the life confidence was increased from 136 cases (31.92%) before treatment to 339 cases (P0.05). The positive rate of morphine was 89.20% (380/426) before treatment and 91.55% (390/426) before treatment, the difference was not significant (X ~ 2 = 0.974, P = 0.55). Conclusion: Methadone maintenance treatment can significantly improve the behavior of patients in HIV prevention process, so that it can actively participate in the treatment, and help to improve the urine test results, with high application value.