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作者在对 HBeAg 阳性的慢性乙型肝炎患者进行类固醇脱离疗法时,对于那些有消化性溃疡病史的病例,合并使用了西米替丁发现很多病例出现血清转化,为此作者专门作了研究,研究对象分4组,第一组6例,男女各3例,平均年龄38岁。慢性活动性肝炎(CAH)3例,未检3例,治疗前 DNA 多聚酶(DNA-P)899cpm,观察9.8个月,本组在类固醇脱离疗法中并用西米替丁。第二组2例,男女各1例,平均年龄28岁。CAH2例,DNA-P310cpm,观察7个月,在类固醇脱离与阿糖腺苷合并疗法中并用西米替丁。第三组20例,男15例,女5例,平均年龄33岁。CAH13例,慢性持续性肝炎(CPH)
When the authors conducted steroid ablation therapy on patients with HBeAg-positive chronic hepatitis B, for those with a history of peptic ulcer, the combination of cimetidine found in many cases of seroconversion, for which the author made a special study Subjects were divided into 4 groups, the first group of 6 patients, 3 males and 3 females, mean age 38 years. 3 cases of chronic active hepatitis (CAH), 3 cases were not tested, DNA polymerase P (DNA-P) 899cpm, observed for 9.8 months, this group in the steroid ablation therapy with cimetidine. The second group of 2 patients, 1 male and 1 female, mean age 28 years old. CAH2 cases, DNA-P310cpm, observed for 7 months, in combination with corticosteroid and valaurodine therapy and cimetidine. The third group of 20 patients, 15 males and 5 females, mean age 33 years. 13 cases of CAH, chronic persistent hepatitis (CPH)