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川芎始载于《神农本草经》,为伞形科植物川芎(Ligusticum chuanxiong Hort.)的干燥根茎,具有活血行气、祛风止痛的功效,其主要有效成分为川芎嗪和阿魏酸等[1,2],由于临床上已使用盐酸川芎嗪和阿魏酸钠的相关制剂,文献[3,4]报道,若以川芎中的组分阿魏酸与川芎嗪配伍使用,其效果比单用的阿魏酸与川芎嗪更为显著,因此,本课题组在组分中药理
Chuanxiong was originally contained in “Shen Nong’s Herbal Classic”, which is the dried rhizome of Ligusticum chuanxiong Hort. It has the effects of promoting blood circulation and expelling gas and expelling wind and relieving pain. Its main active ingredients are ligustrazine and ferulic acid [ 1,2], as clinically used tetramethylpyrazine hydrochloride and sodium ferulate related preparations, reported in the literature [3,4], if the Chuanxiong part of the ferulic acid and ligustrazine used in combination, the effect is more than a single Used ferulic acid and ligustrazine more significant, therefore, our group pharmacology in the components