新生儿出现低钙血症常采取静脉注射钙剂治疗,一般使用葡萄糖酸钙静脉注射。然而,葡萄糖酸钙属高渗溶液,外溢可引起局部软组织的变性、坏死、钙质沉着。对此文献报道较少。现报告一例如下。患儿男,1个月。出生一周时因全血总钙1.35 mmol/L,给予10%葡萄糖酸钙5 ml+10%葡萄糖10 ml用输液泵缓慢静脉注射,每天2次,共5天。右内踝留置BD针,第3天右内踝局部隆起,稍发红,考虑葡萄糖酸钙外溢1~2 ml,遂改换为左侧足背静脉继续输入。右踝未做特殊处理。第5天右内踝针眼处变硬出现破溃,当地医院即给予抗炎治疗 Neonatal hypocalcemia often take intravenous calcium treatment, the general use of calcium gluconate intravenously. However, calcium gluconate is a hypertonic solution that can cause denaturation, necrosis, and calcification of the local soft tissue. Reported less in this literature. Here is an example of the report. Children male, 1 month. One week after birth, whole blood total calcium 1.35 mmol / L, given 10% calcium gluconate 5 ml + 10% glucose 10 ml slow intravenous infusion pump twice a day for 5 days. The right medial malleolar indwelling BD needle, the third day of the local medial malleolus uplift, a little red, consider calcium gluconate spill 1-2 ml, then changed to the left dorsal vein to continue typing. Right ankle without special treatment. On the 5th day, the intraocular injury of the right medial malleolus appeared ulcerated, and the local hospital gave anti-inflammatory treatment