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药物的疗效主要有赖于受体部位药物的生物有效度。生物有效度包括药物的吸收与分布二个过程。四环素的生物有效度受食物与制剂处方所影响。含钙、镁、铝的制酸剂妨碍胃肠道吸收四环素,导致抗菌素的血清浓度降低。作者认为,药物在临床发挥不同疗效的原因,大多数情况是与药物的扩散及胃肠道的吸收有关,因而设计了一个双房室扩
The efficacy of the drug depends mainly on the bioavailability of the drug at the receptor site. Bioavailability includes the absorption and distribution of drugs two processes. The bioavailability of tetracycline is affected by the prescription of food and preparation. Antacids that contain calcium, magnesium, and aluminum block the absorption of tetracycline in the gastrointestinal tract, resulting in a reduction in serum concentrations of antibiotics. The author believes that the drugs in the clinical play a different therapeutic effect, in most cases with the proliferation of drugs and gastrointestinal absorption, and thus designed a dual chamber expansion