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1985年由美国外科感染学会召开的多器官功能衰竭(MOF)综合征专题讨论,内容新颖,从细胞、体液介质、免疫等方面探讨其发病机理,在防治重症外科感染病人合并MOF,具有重要参考价值。 MOF的发病率和分期继急诊手术后MOF的发病率为7～22％、腹腔严重感染手术后占30～50％,其死亡率30～100％。按病人一般情况、心血管、呼吸、肾和肝功能、代谢、血液和中枢神经八个方面分成四期。第一期:临床初检一切正常,进一步发现有轻度呼吸性碱中毒及肾功能早期改变。第二期:病态表现,一般情况欠稳定,心功能为容量依赖性高排量型。有气急、缺氧、低碳
In 1985, the symposium on multiple organ failure (MOF) syndrome held by the American Society of Surgical Infectious Diseases focused on discussing the pathogenesis of MOF syndromes in terms of cellular, humoral mediators and immunity. It is an important reference for the prevention and treatment of MOF syndromes in critically ill surgical patients value. MOF morbidity and staging following the emergency surgery MOF incidence of 7 to 22%, severe abdominal infection after surgery accounted for 30 to 50%, the mortality rate of 30 to 100%. According to the general situation of patients, cardiovascular, respiratory, kidney and liver function, metabolism, blood and central nervous system divided into eight aspects. Phase I: Initial clinical examination of all normal, further found mild respiratory alkalosis and early changes in renal function. Phase II: pathological manifestations, the general situation is not stable, cardiac function is high capacity-dependent displacement type. Acute, hypoxia, low carbon