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本文就复合性放射损伤的临床特点及发病机制作一综述,并对内外照射的远期生物学作用进行了讨论。当γ射线全身照射剂量超过1～2戈瑞就可引起急性放射病。由于吸收剂量的分布特点可产生不同的放射综合症,而放射病的临床过程和结局取决于吸收剂量的大小和照射野内器官的特点。内外γ射线复合作用(复合放射核素)可在机体内产生复杂的病理过程,γ射线全身外照射一次作用是短暂的,相对地其吸收剂量分布亦均匀,而内照射的剂量形成时间较长,其剂量分布特点和剂量形成的强度决定于进入体内的放射性核素的理化特性,被储
This article reviews the clinical features and pathogenesis of composite radiation injury and discusses the long-term biological effects of both internal and external exposure. When the γ-ray total body irradiation dose of more than 1 to 2 Gyre can cause acute radiation sickness. Due to the distribution of absorbed dose can produce different radiation syndrome, and the clinical course and outcome of radiation sickness depends on the size of the absorbed dose and the characteristics of the irradiated organ. Internal and external γ-ray combination (composite radionuclide) can produce complex pathological processes in the body, γ-ray whole body external irradiation is a short-term effect, the relative absorption dose distribution is also uniform, and internal irradiation dose formation time longer , Its dose distribution characteristics and the intensity of dose formation depends on the physical and chemical properties of radionuclides entering the body,