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目的:总结分析我院2009年上半年的药品不良反应(ADR)报告,促进临床合理用药,保障患者用药安全。方法:汇总统计上半年上报的177例ADR,分别从患者年龄、性别、给药途径、临床表现、药品种类、严重的ADR及ADR前10位药品等方面进行统计分析。结果:177例ADR报告中,高年龄段(>60岁)发生率高;男女ADR发生率相当;主要给药途径为静脉滴注(占94.35%);涉及的药品共有87种,其中抗感染药物35种(占40.23%),共82例(占46.33%),位居首位;ADR类型主要为皮肤及其附件损害(占45.76%);新的、严重的ADR 45例(占25.42%);ADR排序第1位的是注射用头孢哌酮舒巴坦。结论:医疗机构必须重视药品不良反应,深入开展ADR监测工作。
OBJECTIVE: To summarize and analyze the report of adverse drug reaction (ADR) in the first half of 2009 in our hospital to promote rational drug use and ensure the safety of patients. Methods: A total of 177 ADRs reported in the first half of the year were collected and analyzed statistically in terms of patient age, sex, route of administration, clinical manifestation, type of drug, serious ADR and top 10 ADR drugs. Results: The incidence of ADR in 177 ADR cases was high in older age group (> 60 years). The incidence rate of ADR in men and women was the same. The main route of administration was intravenous drip (94.35%). There were 87 kinds of drugs involved, of which anti-infective Among them, 35 (40.23%) were drugs (82 cases), accounting for 46.33% of all cases. Among them, ADR types were mainly skin and its accessories (45.76%), 45 cases (25.42%) were new and serious ADRs, ; ADR ranked No. 1 injection of cefoperazone sulbactam. Conclusion: Medical institutions must attach importance to adverse drug reactions and conduct in-depth ADR monitoring.