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目的探讨检测改良胸水常规检查中淋巴细胞/中性粒细胞(L/N)、淋巴细胞绝对值、蛋白定量鉴别结核性胸水和癌性胸水的临床意义。方法选取110例胸腔积液患者,其中结核性胸水65例、癌性胸水45例,胸水常规用迈瑞BC6900仪器体液模式和牛鲍池计数板进行有核细胞计数,分类采用瑞-姬染色后显微镜CX-21下计数100个细胞;ADA采用AU5400连续监测法检测;CEA采用电化学发光法检测;蛋白采用奥森多5600干化学法。结果 L/N、淋巴细胞绝对值、蛋白定量在结核性胸水中的含量高于癌性胸水,差异有统计学意义(P<0.05)。L/N、淋巴细胞百分比、淋巴细胞绝对值、蛋白定量、胸水ADA的ROC曲线下面积分别为0.566、0.769、0.923、0.772、0.955。结论改良胸水常规检测对于结核性胸水和癌性胸水具有良好的鉴别价值。
Objective To investigate the clinical significance of detecting lymphocyte / neutrophil (L / N), lymphocyte absolute value and protein quantitatively identifying tuberculous pleural effusion and cancerous pleural effusion in routine hydrothorax test. Methods Totally 110 patients with pleural effusion were enrolled. Among them, 65 cases of tuberculous pleural effusion and 45 cases of cancerous pleural effusion were enumerated. The pleural effusion was routinely counted in nucleated cells with Mindray BC6900 instrument and the abalone pool counting plate. -21 under the count of 100 cells; ADA AU5400 continuous monitoring test; CEA electrochemical detection; protein using Orson’s 5600 dry chemistry. Results The absolute values of L / N, lymphocytes and protein in tuberculous pleural effusion were higher than those in cancerous pleural effusion, the difference was statistically significant (P <0.05). The area under the ROC curve of L / N, lymphocyte percentage, lymphocyte absolute value, protein quantitation and pleural effusion ADA were 0.566, 0.769, 0.923, 0.772 and 0.955, respectively. Conclusion The routine examination of modified pleural effusion has good differential value for tuberculous pleural effusion and malignant pleural effusion.