本文对20例小儿急性白血病进行了外用血NK细胞活性的测定。男13例、女7例，年龄4～13岁。其中急淋5例、急非淋15例。结果表明：急性白血病患儿NK细胞活性明显下降，与对照组（正常健康儿男12、女15，年龄为5～13岁）相比有显著差异，P＜0.05，并与文献报道相符。文中指出，在白血病的治疗过程中从其缓解、复发时NK细胞活性变化的检测，有益于对病情的了解、感染的存在等估评。例数偏少有待进一步阐明。 In this paper, 20 cases of pediatric acute leukemia for the determination of NK blood cell activity. 13 males and 7 females, aged 4 to 13 years. Five cases of acute leaching, acute non-leaching 15 cases. The results showed that the NK cell activity of children with acute leukemia was significantly decreased compared with the control group (normal healthy children 12, 15 female, aged 5 to 13 years) were significantly different, P <0.05, and in line with the literature. The article pointed out that in the course of treatment of leukemia from its mitigation, detection of NK cell activity changes during recurrence, beneficial to the understanding of the disease, the presence of infection and other estimates. A small number of cases to be further clarified.