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喹诺酮（quinolone）于60年代早期开始应用于临床治疗肠杆菌引起的泌尿道感染。近年来大量的资料介绍新的、更强抗菌活性的萘啶酸（naldi-xic acid）的衍生物氟喹诺酮类（fluorinated pui-nolones）。为此，1987年7月在日内瓦举行了新喹诺酮国际讨论会，1987年6月英国药学会也举行了喹诺酮专题讨论会，本文拟就有关问题作一概述。
Quinolones (quinolone) in the early 60’s began to be used in the clinical treatment of Enterobacteriae-induced urinary tract infections. In recent years a lot of information on the new, more antibacterial activity of naldic acid (naldi-xic acid) derivative fluoroquinolones (fluorinated pui-nolones). To this end, an international seminar on new quinolones was held in July 1987 in Geneva, and a quinolone seminar was held in June 1987 by the British Pharmaceutical Association. The paper intends to give an overview of the relevant issues.