新生儿持续肺动脉高压(persistent pulmonary hypertension of the newborn,PPHN)是指生后肺血管阻力持续性增高,肺动脉压超过体循环动脉压,胎儿型循环过渡到新生儿型循环发生障碍所导致的危重急症,多见于足月儿或过期产儿。按病因分为原发性及继发性,原发性为不明原因的PPHN,继发性常见于胎粪吸入综合征或新生儿呼吸窘迫综合征等。按发病机制分为肺血管发育不全、肺血管发育不良 Persistent neonatal pulmonary hypertension (persistent pulmonary hypertension of the newborn, PPHN) refers to the persistent increase of post-natal pulmonary vascular resistance, pulmonary arterial pressure exceeds systemic arterial pressure, fetal cycle transition to neonatal cycle disorders caused by critical illness, More common in term infants or expired children. According to the cause of the disease is divided into primary and secondary, primary unexplained PPHN secondary common in meconium aspiration syndrome or neonatal respiratory distress syndrome. According to the pathogenesis is divided into pulmonary vascular hypoplasia, pulmonary vascular dysplasia