1984年本实验室用甲基碘酸乙酯处理黑腹果蝇(Drosophila melanogaster)的标准野生型品系Oregon K雄蝇并得到2个突变型:(y)和(yB).通过一系列遗传杂交实验培育出2个适于进行非整倍体检测试验的品系:(yB/Yy~+)和(yw/yw)。我们曾进行了15种化合物在该测试系统中的诱变性试验,对该测试系统的敏感度进行了初步验证(见《癌变·畸变·突变》1989;1(1):38)。为了进一步验证该测试系统对致癌物的敏感度,我们又用其他9种化合物进行了试验。这9种化合物是:甲基苄肼、笨并 In 1984, our laboratory treated the standard wild-type Oregon K male flies of Drosophila melanogaster with methyl methyl iodide and got two mutant types: (y) and (yB) .Through a series of genetic crosses Two strains suitable for aneuploidy test were obtained: (yB / Yy ~ +) and (yw / yw). We conducted a mutagenicity test of 15 compounds in this test system, and the sensitivity of this test system was preliminarily verified (see Cancer Mutation and Mutagenesis 1989; 1 (1): 38). In order to further verify the sensitivity of the test system to carcinogens, we tested with nine other compounds. The nine compounds are: procarbazine, stupid