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目的分析侧支循环建立患者的临床资料,寻求影响其形成的因素和临床特征。方法回顾性收集北京大学第三医院2005-09-01—2007-08-31第一次行冠状动脉造影记录,经冠状动脉造影确诊有1根冠状动脉完全闭塞,有侧支循环建立的住院病例52例,将无侧支循环建立病例52例作为对照组,分析其临床资料。结果使用Logistic回归分析患者一般临床资料、既往病史、生活习惯、目前服用药物与侧支循环建立的关系,与侧支循环建立相关的为既往患有糖尿病病史以及运动、饮酒,回归系数分别为0.408、0.483、0.197(P<0.05)。对其中不稳定心绞痛患者进行分析,心电图提示心肌缺血占28.6%,超声心动图提示室壁运动减弱占16.7%,运动平板试验阳性者占100%,负荷核素心肌显像提示灌注缺损占100%。结论侧支循环的建立与糖尿病、饮酒、运动相关,有侧支循环建立患者行心电图、超声心动图的阳性率低。
Objective To analyze the clinical data of patients with collateral circulation in order to find out the factors and clinical characteristics that affect their formation. Methods The retrospective collection of Peking University Third Hospital 2005-09-01-2007-08-31 The first line of coronary angiography recorded by coronary angiography confirmed a complete occlusion of coronary arteries, collateral circulation established inpatient 52 cases, no collateral circulation established cases of 52 cases as a control group, analysis of clinical data. Results Logistic regression analysis was used to analyze the general clinical data, past medical history, lifestyle, the current relationship between drug taking and collateral circulation, the history of diabetes mellitus associated with collateral circulation and the exercise, alcohol consumption and regression coefficients of 0.408 , 0.483,0.197 (P <0.05). Among them, unstable angina patients were analyzed, electrocardiogram showed myocardial ischemia accounted for 28.6%, echocardiography showed wall motion decreased 16.7%, exercise treadmill test positive 100%, load nuclide myocardial imaging showed perfusion defect accounted for 100 %. Conclusions The establishment of collateral circulation is associated with diabetes, alcohol consumption and exercise. Patients with collateral circulation have established electrocardiogram and the positive rate of echocardiography is low.