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目的:观察肠外高营养对重症溃疡性结肠炎临床治疗效果。方法:对119例重症溃疡性结肠炎患者采取肠外静脉补充足够的营养,完全胃肠道休息。同时于治疗前后进行组织学检查。结果:经过4周治疗后临床痊愈36例(30.3%),好转65例(54.6%),无效18例(15.1%),总有效率84.9%。全部患者血清谷草转氨酶和谷丙转氨酶在正常范围,血清白蛋白治疗后明显好转(P<0.05),组织学也明显改善。结论:重症溃疡性结肠炎肠外静脉高营养疗法是一种安全、有效可行的方法,同时可以促进组织学恢复。
Objective: To observe the clinical effect of extra-parenteral nutrition on severe ulcerative colitis. Methods: 119 cases of severe ulcerative colitis patients take parenteral vein supplementation of adequate nutrition, complete gastrointestinal rest. At the same time before and after treatment for histological examination. Results: After 4 weeks of treatment, 36 cases (30.3%) recovered clinically, 65 cases (54.6%) were improved, 18 cases (15.1%) were ineffective, and the total effective rate was 84.9%. All patients serum AST and ALT in the normal range, serum albumin significantly improved after treatment Conclusion: Severe ulcerative colitis parenteral nutrition therapy is a safe, effective and feasible method, and can promote histological recovery.