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以微量生化法测定１５９例各年龄组的正常对照、良性胃病、胃癌患者血浆６种维生素及２２例胃癌手术标本各部位粘膜细胞内４种维生素、３０例慢性萎缩性胃炎胃镜活检粘膜细胞内β－胡萝卜素的含量。结果发现，正常健康老人和老年胃癌患者维生素Ｂ１２含量低于同组中青年人（Ｐ＜０．０５）；老年胃癌患者血浆β－胡萝卜素水平明显低于良性胃病和健康对照组（Ｐ＜０．０５）。胃癌患者癌区粘膜细胞内β－胡萝卜素与外周正常区域细胞内含量之差及慢性萎缩性胃炎活检粘膜细胞内的含量皆与年龄呈负相关。说明老年胃病患者血浆维生素的改变以维生素Ｂ１２和β－胡萝卜素为主；胃癌区粘膜细胞内β－胡萝卜素的降低幅度不如中青年明显，而老年慢性萎缩性胃炎患者该维生素又低于中青年。
The results of microbiochemical assay showed that there were 159 cases of normal control, benign stomach disease, 6 kinds of vitamins in plasma of gastric cancer patients and 4 vitamins in mucosal cells in 22 cases of gastric cancer operation specimens, 30 cases of chronic atrophic gastritis gastroscopy biopsy mucosal β Carotene content. The results showed that the content of vitamin B12 in normal healthy elderly and elderly patients with gastric cancer was lower than that in young people in the same group (P <0.05). The plasma β-carotene level in elderly patients with gastric cancer was significantly lower than that in benign stomach and healthy controls .05). The difference between intracellular contents of β-carotene and normal peripheral mucosal cells in mucosal cells of gastric cancer patients and the contents of mucosal cells in chronic atrophic gastritis biopsies were negatively correlated with age. The changes of plasma vitamins in elderly patients with gastric disorders mainly vitamin B12 and β-carotene; gastric mucosal cells in β-carotene decreased less than in young and middle-aged, while elderly patients with chronic atrophic gastritis and vitamins and then lower than middle-aged .