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阿斯匹林(ASA)已广泛应用于心脑血管病的预防,其最适剂量一直存有争议。我们曾系统观察研究了不同剂量ASA对脑梗塞患者血小板聚集(PAgT)、血栓烷素A_2(TXA_2)及前列环素(PGI_2)的影响。为了进一步验证ASA的临床疗效,我们组织了16家医院对815例病人进行了1～5年的随访观察,现将结果报告如下。
Aspirin (ASA) has been widely used in the prevention of cardiovascular and cerebrovascular diseases, the optimal dose has been controversial. We systematically observed the effects of different doses of ASA on platelet aggregation (PAgT), thromboxane A 2 (TXA 2) and prostacyclin (PGI 2) in patients with cerebral infarction. To further validate the clinical efficacy of ASA, we conducted a follow-up of 815 patients in 1 to 5 years in 16 hospitals, and the results are reported below.