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了解武汉地区近年来肝硬化发病情况、常见病因、主要并发症、病死率和相关因素。方法 采用回顾性调查方法 ,对武汉地区所属二级、三级医院 ,1992～ 1996年 5年间所有住院确诊为肝硬化的病历资料作调查分析。结果 42家医院 5年住院肝硬化患者 8183例 ,占肝病患者的 10 .7%。武汉地区年均肝硬化住院率为 2 3/ 10万。 1996年肝硬化患者比 1992年上升 5 7% ,而同期肝病住院患者下降 33%。病因中病毒性肝炎占 75 .4% ,血吸虫病为 18.0 % ,酒精性肝硬化为 5 .9% ,其它病因为 0 .5 % ,5年中这一比例无明显变化。失代偿肝硬化 70 0 6例 ,占 85 .6 % ,腹水 4716例 ,占 6 7.3 % ,其次是上消化道出血 16 5 4例 ,占 2 3.6 % ,肝性脑病占 9.7% ,感染占 8.8%。武汉城区肝硬化年死亡率分别为 8.5 / 10万。结论 本地区肝硬化患者逐年增多 ,病死率高 ,危害大。加强肝硬化防治 ,降低发病率 ,提高患者生活质量及存活率有重要现实意义
To understand the incidence of cirrhosis in Wuhan in recent years, common causes, major complications, mortality and related factors. Methods A retrospective survey was conducted to investigate the data of medical records of all the hospitalized patients with cirrhosis admitted to the second and third level hospitals in Wuhan and the five years from 1992 to 1996. Results 8,183 hospitalized cirrhosis patients in 5 hospitals in 42 hospitals accounted for 10.7% of the patients with liver diseases. The annual average hospitalization rate of liver cirrhosis in Wuhan is 23 / 100,000. In 1996, the number of cirrhotic patients increased by 57% over 1992, while the number of hospitalized patients with liver diseases decreased by 33% in the same period. The cause of viral hepatitis accounted for 75.4%, schistosomiasis was 18.0%, alcoholic cirrhosis was 5.9%, other causes were 0.5%, 5 years in this ratio no significant change. 706 cases of decompensated cirrhosis, accounting for 85.6%, 4716 cases of ascites, accounting for 7.3%, followed by 165 cases of upper gastrointestinal bleeding, accounting for 23.6%, hepatic encephalopathy accounted for 9.7%, accounting for infection 8.8%. The annual mortality rate of liver cirrhosis in Wuhan is 8.5 / 100,000 respectively. Conclusion The number of patients with cirrhosis in the area increased year by year, with high mortality and great harm. To strengthen the prevention and treatment of cirrhosis, reduce morbidity and improve patient quality of life and survival rate of great practical significance