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应用流式细胞术和细胞免疫荧光染色技术，对胃癌前病变和胃癌细胞Ｐ２１￣（ｒａｓ）的表达量进行了定量研究，并分析了Ｐ２１￣（ｒａｓ）的表达量与ＤＮＡ倍体和细胞增殖指数的关系。结果表明：胃癌细胞Ｐ２１￣（ｒａｓ）表达量（荧光指数ＦＩ）明显高于胃癌前病变的表达量，并发现Ｐ２１￣（ｒａｓ）表达的荧光指数随组织学分级增高而升高，ＤＮＡ倍体与Ｐ２１￣（ｒａｓ）表达量有密切关系。
The expression of P21 ̄ (ras) in gastric precancerous lesions and gastric cancer cells was quantitatively studied by flow cytometry and immunofluorescence staining, and the expression of P21 ̄ (ras) and DNA ploidy and cell proliferation were analyzed. The relationship of the index. The results showed that the expression of P21 ̄ (ras) in gastric cancer cells was significantly higher than that in precancerous lesions, and the fluorescence index of P21 ̄ (ras) expression was increased with histological grading, and DNA ploidy was found. It is closely related to the expression of P21 ~ (ras).