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目的：通过测定手术前后血清白细胞介素6（IL－6）的水平，探讨恶性肿瘤的早期诊断。方法：采取双抗体夹心ELISA方法，对30例良、恶性卵巢肿瘤患者手术前后进行血清IL－6水平检测。结果：恶性卵巢上皮癌患者手术前后血清IL－6水平有明显变化，经统计学分析差异有显著性（P＜0．05）。结论；恶性卵巢上皮癌患者术前血清IL－6水平明显增高，术后血清IL－6水平很快恢复正常。卵巢上皮癌患者术后随访血清IL－6水平，可作为预测卵巢癌预后参考指标。
Objective: To explore the early diagnosis of malignant tumor by measuring the level of serum interleukin-6 (IL-6) before and after surgery. Methods: Serum IL-6 levels were measured before and after surgery in 30 patients with benign and malignant ovarian tumors by double-antibody sandwich ELISA. Results: The level of serum IL-6 in patients with malignant ovarian epithelial carcinoma before and after surgery had significant changes, and the difference was statistically significant (P <0.05). Conclusions; Preoperative serum IL-6 levels in patients with malignant ovarian epithelial carcinoma were significantly increased, and postoperative serum IL-6 levels returned to normal quickly. Postoperative follow-up of serum IL-6 levels in patients with epithelial ovarian cancer can be used as a reference index to predict the prognosis of ovarian cancer.