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大量临床试验表明,对于可切除的直肠癌病人,如果手术结合放疗和化疗,局部控制率和总存活率可明显升高。本文的目的在于强调单用手术方法治疗某些直肠癌病人有其局限性,并对辅助疗法的优缺点进行评议。作者将列举几项近期进行的主要试验,就多种形式治疗有关的一些问题。建议今后的研究方向。单纯手术淋巴结阴性的直肠癌病人71～93%可通过根治性切除而治愈,而区域淋巴结浸润者仅29～41%可手术治愈。根治性手术与辅助放疗
A large number of clinical trials have shown that, for resectable rectal cancer patients, the local control rate and overall survival rate can be significantly increased if combined with radiotherapy and chemotherapy. The purpose of this article is to emphasize that surgical treatment of some patients with rectal cancer has its limitations and to evaluate the advantages and disadvantages of adjuvant therapy. The author will list several recent major trials on some of the issues related to multiple forms of treatment. Suggest future research directions. 71% to 93% of surgically-negative lymph node-negative rectal cancer patients can be cured by radical resection. Only 29% to 41% of regional lymph node infiltration patients can be cured. Radical surgery and adjuvant radiotherapy