小儿流行性脑膜炎154例临床分析

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1、本科自1954年1月1日至59年4月30日止共收容小儿流行性脑膜炎患者154例住院,占同时期住院病儿之2.1%。每年发病最多之月份为2、3、4三个月,其中3月份为最多,计42例、占27.3%。 2、男与女与比約为3:2。年龄最小为52天,最大12岁,平均4岁3个月。以12个月以內之乳嬰为最多,計46例、占29.8%。 3、入院时主要症状以发燒为最多,計151例占全組之98.1%,其次为嘔吐124例(80.5%), 头痛59例(38.3%)嗜睡57例(37.0%),昏迷49例(31.8%)。发病时間愈长出现昏迷之病例愈多。主要体征为:神志昏迷或半昏迷者67例(43.5%),呼吸有改变或33例(21.4%),皮肤有出血点者73例(47.4%),前囱飽满26例(16.9%),頸抵抗137例(88.9%),克匿格氏征阳性者67例(51.3%),布氏征阳性者76例(49.4%)。 4、脊脑液中白細胞总数在500以上者138例(89.6%),其多形核球在71%以上者141例(91.6%。糖减少,蛋白质增加。122例作过涂片檢查,23例(占檢查組18.8%)找到脑膜炎双球菌。脊脑液培养88例,发现有脑膜炎双球者15例,占檢查組17.0% 5、除一例外均用磺胺嘧啶及青霉素合并治疗。痊愈无后遺者111例(72.0%)。 6、本組中共死亡11例,9例在入院24小时內死亡,校正后死亡率为1.3%。以2月份死亡率最高,共5例,占同月发病病例27例之18.5%。年龄以4—5岁为最多,乳嬰之发病率虽高,治愈率亦高。死亡病例之全身中毒状况较重,神志均不清楚,3例始終不烧,2例颈部柔軟。脊脑液中糖較痊愈病例为少,主要死因为病情严重,呼吸衰竭。 1, undergraduate from January 1, 1954 to April 30, 59, only a total of 154 cases of children with meningitis admitted to hospital, accounting for 2.1% of hospitalized children in the same period. The most frequent monthly incidence of 2,3,4 for three months, of which the largest in March, accounting for 42 cases, accounting for 27.3%. 2, male to female ratio of about 3: 2. The youngest is 52 days, a maximum of 12 years old, an average of 4 years and 3 months. In 12 months, most of the babies and babies, accounting for 46 cases, accounting for 29.8%. The main symptom of admission was fever, accounting for 98.1% of the whole group, followed by vomiting in 124 cases (80.5%), headache in 59 cases (38.3%), sleepiness in 57 cases (37.0%) and coma in 49 cases (31.8%). The longer the onset of coma, the more cases. The main signs were: 67 cases (43.5%) with conscious or semi-coma, breathing change or 33 cases (21.4%), 73 cases (47.4%) with bleeding and 26 cases (16.9% , 137 cases (88.9%) of cervical resistance, 67 cases (51.3%) of positive Keccin’s syndrome and 76 cases (49.4%) of positive Buch’s sign. There were 138 cases (89.6%) with more than 500 leukocytes in the spinal fluid and 141 cases (71.6%) with more than 71% pleochroism bulbs. Cases (accounting for 18.8% of the inspection group) to find meningococcus .In the 88 cases of spinal fluid culture, found that there are 15 cases of meningitis double ball, accounting for 17.0% of the examination group 5, with one exception, both sulfadiazine and penicillin combined treatment. There were 111 cases (72.0%) who recovered without hemorrhage.6.There were 11 cases of death in this group, 9 cases died within 24 hours after admission, and the corrected death rate was 1.3% .The highest mortality in February was 5 cases Incidence of the same month, 27 cases of 18.5% .Age to 4-5 years of age, the incidence of infant and baby is high, the cure rate is also high.The death of the case of severe systemic poisoning, consciousness are not clear, three cases never burn , 2 cases of soft neck.The spinal fluid in the recovery of less sugar than the cases, the main cause of death was serious illness, respiratory failure.
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