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[目的]测定假尿音在食管癌贲门癌病人尿中的含量,分析其临床价值。[方法]应用高效液相色谱法对41例食管癌病人、21例贲门癌病人检测尿PD/Cr数值,并与对照组进行比较。[结果]食管癌贲门癌病人尿假尿苷水平显著高于正常人(P<0.01),较血清CEA‘β_2-MG、SA等肿瘤标志物灵敏;尿假尿奇联合血清CEA检测可提高检测阳性率。[结论]尿假尿着可作为食管癌贲门癌病人的肿瘤标志物,动态测定对手术预后判断及疗效评价有积极意义,具有一定的参考价值。
[Objective] To determine the content of urine urine in urine of esophageal and cardiac cancer patients and analyze its clinical value. [Methods] The urinary PD/Cr values of 41 patients with esophageal cancer and 21 patients with cardiac cancer were measured by high performance liquid chromatography and compared with the control group. [Results] The level of urinary Pseudouridine in patients with esophageal and cardiac cancer was significantly higher than that in normal subjects (P<0.01). It was more sensitive than serum CEA’β_2-MG, SA and other tumor markers. Urinary diuretic and serum CEA could be detected. Increase the positive rate of detection. [Conclusion] Urine urination and urination can be used as tumor markers in esophageal and cardiac cancer patients. The dynamic measurement has positive significance for the evaluation of prognosis and curative effect. It has certain reference value.