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本文报告“水源高碘地方性甲状腺肿并发甲状腺机能亢进”(以下简称水源高碘甲肿甲亢),在高碘地甲肿患者中检出率高达7.76%。临床上有甲状腺Ⅱ°—Ⅲ°弥漫性肿大,有典型甲亢的症状和体征。甲状腺吸~(131)碘率较当地居民明显增高,血清 T_3、T_4偏高,但 TSH 基本正常,有的甚至偏低,T_3抑制试验不抑制,有的 TGAb、TMAb 为阳性,有的 TPO (过氧化物酶活性)增高。病理检查:具有巨滤泡性胶样甲状腺肿和甲状腺机能亢进两组病理学和超微结构特征。
This report, “High-iodine iodine endemic goiter complicated by hyperthyroidism” (hereinafter referred to as high-iodine, iodine, thyroid, hyperthyroidism), in high-iodine patients with a detection rate of up to 7.76%. Clinical thyroid Ⅱ ° -Ⅲ ° diffuse enlargement, there are typical symptoms and signs of hyperthyroidism. Thyroid uptake of 131I was significantly higher than the local residents, serum T_3, T_4 high, but TSH basically normal, and some even low, T_3 inhibition test does not inhibit, and some TGAb, TMAb positive, and some TPO ( Peroxidase activity) increased. Pathological examination: with giant follicular gel-like goiter and hyperthyroidism two groups of pathological and ultrastructural features.