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氯毒素治疗腸伤寒,一致公认为目前最有效的药物,戴自英氏报告,伤寒的死亡率由20.3%减至7.3%,但氯毒素对肠伤寒的併发症尚不能控制,在治程中,肠出血仍有发现,据文献載,国外McCrae氏报告7%,St(?)ast氏为21%,国内戴自英氏为13%,王胜淼氏为16%,本院内科59年1—5月经确诊为肠伤寒的共收治45例,内用中药协定处方治疗共20例,用中医辨症施治的共8例,用氯霉素治疗共17例,肠出血共3例,占6.6%,比各地的併发率为低,而3例均系用氯霉素治疗组的,应用中药治疗,未发现肠出血,同时复发率亦比氯霉素为低(中药治肠伤寒报告尚未发表)。肠出血的病理学基础肠伤寒最显著和最特殊和变化为肠壁的集合淋巴结和淋巴滤泡,肠系膜淋巴结及脾脏。其变化具有周期性的,病变发展的一定阶段和疾病的一定程期相符合,可分为5期:
Chlorotoxin treatment of enteral typhoid, is generally recognized as the most effective drug at the moment, Dai Zi Ying reported that the mortality of typhoid fever from 20.3% to 7.3%, but the chlorotoxin on the complications of typhoid fever can not control, in the governance process, Intestinal hemorrhage is still found, according to literature, foreign McCrae’s report 7%, St (?)ast’s 21%, domestic wear from Britain’s 13%, Wang Sheng’s 16%, the hospital’s internal medicine 59 years 1-5 months diagnosed A total of 45 cases of enteral typhus were treated, 20 cases were treated with Chinese medicine prescriptions, 8 cases were treated with TCM syndrome differentiation, 17 cases were treated with chloramphenicol, and 3 cases were intestinal hemorrhage, accounting for 6.6%. The rate of concurrency was low in all areas, and in all cases in the chloramphenicol-treated group, no intestinal bleeding was found and the recurrence rate was lower than that of chloramphenicol (Chinese medicine has not yet been published). The pathological basis of intestinal hemorrhage is the most significant and most specific of intestinal typhoid and changes to the intestinal wall of the collecting lymph nodes and lymphoid follicles, mesenteric lymph nodes and spleen. The changes are cyclical, and certain stages of the disease development are consistent with certain stages of the disease and can be divided into five phases: