糖尿病的慢性并发症包括大血管病变和周围神经病变。大血管病变主要表现为动脉粥样硬化,肢体外周动脉粥样硬化(常以下肢动脉病变为主),表现为下肢疼痛、感觉异常、间歇性跛行,严重供血不足可导致肢体坏疽[1]。糖尿病周围神经病变的发生和发展是微血管病变、代谢异常和神经血液供应障碍共同参与的结果。1资料与方法1.1一般资料选取2012-2015年住院糖尿病患者48例,女26例,男22例,年龄49~80岁;糖尿病病程6~20年,不同 Chronic complications of diabetes include macrovascular disease and peripheral neuropathy. Major vascular lesions atherosclerosis, peripheral atherosclerosis (often lower extremity arterial lesions), manifested as lower extremity pain, sensory abnormalities, intermittent claudication, severe lack of blood supply can lead to limb gangrene [1]. The occurrence and development of diabetic peripheral neuropathy result from the joint involvement of microvascular disease, metabolic disorders and neurological blood supply disorders. 1 Materials and Methods 1.1 General Information selected from 2012 to 2015 inpatients with diabetes 48 cases, 26 females, 22 males, aged 49 to 80 years; duration of diabetes 6 to 20 years, different