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本品为白色结晶或结晶性粉末,无味。极微溶于水及乙醚,微溶于氯仿,溶于乙醇。熔点180℃。药理作用:霉康唑为一高效和安全的广谱抗霉菌药物,供口服、外用及静脉注射,也可根据感染部位的不同,通过气管雾化吸入和滴入如膀胱滴入或肾盂导管给药。对致病性霉菌几乎都有作用,其抑菌浓度为0.1～0.2μg/ml;杀菌浓度为10μg/ml。本品除对霉菌及酵母菌有效外,革兰氏阳性菌特别是球菌对它较为敏感。生长期金黄色葡萄球菌在0.2μg/ml 时即可被抑制,对炭疽杆菌也有效。霉康唑为目前抗霉菌药物中抗菌活性最强的一种药物。
This product is white crystal or crystalline powder, tasteless. Very slightly soluble in water and ether, slightly soluble in chloroform, soluble in alcohol. Melting point 180 ℃. Pharmacological effects: Meconazole is an efficient and safe broad-spectrum anti-fungal drug for oral, topical and intravenous injection, but also according to the different parts of the infection by inhalation and instillation of the trachea such as bladder drop or renal catheterization medicine. Almost all of the pathogenic fungi have an effect, the antibacterial concentration of 0.1 ~ 0.2μg / ml; bactericidal concentration of 10μg / ml. This product is effective in addition to mold and yeast, Gram-positive bacteria, especially cocci more sensitive to it. Growth Staphylococcus aureus at 0.2μg / ml can be inhibited, also against Bacillus anthracis. Meconazole is currently the most active antimicrobial drug in antimycotics.