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Zidovudine是一种治疗艾滋病或与之有关综合征的药物,由于本品需频繁给药,艾滋病人每年每人要花约8000美元。在本品的给药方案中加人丙磺舒可使其半衰期增加近一倍。为了确定丙磺舒或硫酸奎宁是否可降低本品的清除率而不降低总的血药浓度以减少用药频率,已作了规模试验。因本品的半衰期只有一小时,目前大多数患者必须每4小时服用一次,每次200mg。 8名患AIDS或ARC的患者,开始每4小时单
Zidovudine is a medicine for the treatment of AIDS or related syndromes. Because of its frequent application, AIDS patients spend about $ 8,000 per person per year. In this product dosing program probenecid can make its half-life nearly doubled. In order to determine whether probenecid or quinine sulfate can reduce the clearance of the goods without reducing the total plasma concentration to reduce the frequency of medication, has been a scale test. Due to the half-life of this product is only one hour, most patients must take every 4 hours once every 200mg. Eight patients with AIDS or ARC started single every 4 hours