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目的应用组织同步显像(TSI)研究冠心病患者左心室心肌运动非同步性和速度特征及其临床意义。方法采用TSI技术对30例冠心病患者(病例组)和30例正常人(对照组)的左心室心肌进行检测,获取左心室各节段心肌长轴方向的组织运动图像,测量各节段心肌达峰值速度时间和峰值速度。结果对照组各节段心肌运动同步性较好,彩色编码多为均一分布的绿色,仅少数节段表现为浅黄色;病例组各节段心肌同步运动规律消失,心肌彩色编码表现为绿～黄～红明显不均,编码为黄色或红色的节段数明显增多(P<0.005)。病例组前壁及室间隔各节段平均达峰值速度时间较对照组增高,差别具有显著性意义(P<0.001)。病例组峰值速度从基底到心尖段逐渐递减的梯度样分布规律消失,前壁各节段及室间隔瓣环、基底段、中间段平均峰值速度较对照组降低(P<0.05)。结论TSI是一种无创伤性定量评价局部心肌达峰值速度时间和峰值速度的新方法,对直观、快速判断心肌缺血及梗死节段有重要价值。
Objective To study the non-synchronous and velocity characteristics of left ventricular myocardial motion in patients with coronary heart disease (CHD) using tissue synchronous imaging (TSI) and its clinical significance. Methods Thirty patients with coronary heart disease (case group) and 30 normal subjects (control group) were subjected to TSI to detect the left ventricular myocardium in the long axis of the left ventricular. Peak speed time and peak speed. Results Compared with the control group, the synchronization of myocardial motion was good. Most of the color coding was green with uniform distribution. Only a few segments showed light yellow color. The myocardial synchronous motion disappeared in each segment of the case group. The myocardial color coding showed green to yellow ~ Red markedly uneven, the number of segments coded yellow or red increased significantly (P <0.005). The mean peak velocity of anterior wall and interventricular septum in case group was higher than that in control group, the difference was significant (P <0.001). In the case group, the gradient distribution of peak velocity gradually disappeared from basement to apical segment disappeared. The average peak velocities of each segment of anterior wall and septal annulus, basement segment and middle segment were lower than those of control group (P <0.05). Conclusion TSI is a new non-invasive quantitative assessment of local myocardial peak velocity time and peak velocity of a new method for visual and rapid assessment of myocardial ischemia and infarction segment has important value.