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奥沙利铂为第三代抗肿瘤药物,其抗瘤谱广,近年来国内有文献报道本品致过敏反应,现概述如下。马金兰等报道,患男,60岁,因乙状结肠癌术后给予奥沙铂150mg+5%GS250ml静滴,滴注过程中患者全身皮肤瘙痒,即停药,予抗过敏对症治疗后,症状缓解[1]。郭凤玲等报道,患女,52岁因直肠癌伴卵巢转移给予本品静滴,5min后患者突然出现胸闷、头晕、颈部有痒感,随之出现呼吸困难、面色苍白,神志不清,即予抢救,20min后症状完全消失,生命体征恢复正常[2]。
Oxaliplatin is the third generation of anti-tumor drugs, its anti-tumor spectrum is broad, in recent years, there are reports of allergic reactions caused by this product, are summarized as follows. Ma Jinlan and other reports, suffering from male, 60 years old, due to sigmoid colon surgery given oxaliplatin 150mg +5% GS250ml intravenous drip, systemic skin pruritus patients during the infusion, that is, to anti-allergic symptomatic treatment, the symptoms were relieved [1]. Guo Fengling and other reports, suffering from women, 52-year-old because of rectal cancer with ovarian metastasis to give this product intravenous infusion, 5min after sudden chest tightness, dizziness, neck itching, accompanied by breathing difficulties, pale, unconscious To rescue, 20min after the symptoms completely disappear, vital signs returned to normal [2].