卵巢恶性肿瘤是女性生殖器三大恶性肿瘤之一,因卵巢位于盆腔内,癌早期无症状,一旦出现临床症状,常失去治疗时机,故急需寻找一种早期正确诊断的方法。近年研究发现卵巢癌患者血清中含有肿瘤相关因子,来源于原发肿瘤的DNA。由于血清标本来源方便和非侵入性等优点逐步替代组织学肿 Ovarian malignant tumor is one of the three major malignant tumors in female genitalia. Because ovary is located in the pelvic cavity, the early stage of carcinoma is asymptomatic. Once the clinical symptoms appear, it often loses the opportunity for treatment. Therefore, it is urgent to find an early correct diagnosis method. Recent studies have found that ovarian cancer patients contain tumor-associated serum, derived from the primary tumor DNA. Due to the convenience of the source of serum samples and non-invasive advantages such as the gradual replacement of histological swelling