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收治系统性红斑狼疮合并妊娠21例,其中合并妊高征6例(286%),胎盘功能不全(IUGR)6例(286%),继发贫血5例(238%),早产3例(143%),无凝血功能障碍,妊高征均发生于SLE肾型患者,有3例妊高征患者同时伴有胎盘功能不全。妊娠可加重SLE,尤其是SLE肾型,且合并妊高征。早产率在本组研究中为143%,与以往文献报道(15%)相似。用强的松预防SLE恶化,控制SLE活动疗效肯定。21例SLE孕妇全部服用强的松,对合并妊高征者增大强的松剂量,母婴预后良好
Twenty-one patients with systemic lupus erythematosus complicated by pregnancy were included, including 6 cases (28.6%) with PIH, 6 cases (28.6%) with placental insufficiency (IUGR), 5 cases (23.8%) with secondary anemia, , 3 cases of preterm delivery (143%), no coagulation dysfunction, pregnancy-induced hypertension occurred in patients with SLE nephropathy, 3 cases of PIH accompanied by placental insufficiency. Pregnancy can aggravate SLE, especially SLE kidney type, and the merger of pregnancy-induced hypertension. Preterm birth rate in this study was 14 3%, similar to the previous literature (15%). With prednisone to prevent deterioration of SLE, control of SLE activity sure effect. 21 cases of SLE pregnant women taking prednisone all, combined with PIH increased prednisone dose, the mother and child prognosis is good