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[目的]认识双硫醒样反应的发病机制、临床表现、救治方法,预防使用部分头孢类、甲硝唑、呋喃唑酮等药物后双硫醒样反应的发生。[方法]对32例出现双硫醒样反应的病例进行临床救治。[结果]32例出现双硫醒样反应的病例临床表现不尽相同,症状轻重不一,治疗方法各异。[结论]使用头孢类、甲硝唑、呋喃唑酮等药物后易出现双硫醒样反应,在使用头孢类、甲硝唑、呋喃唑酮等药物期间不宜食用含酒精食物。
[Objective] To understand the pathogenesis, clinical manifestation and treatment of disulfide-wake-like reaction, and to prevent the occurrence of disulfide-like wake-up reaction after using some cephalosporins, metronidazole, furazolidone and other drugs. [Methods] Thirty-two cases of occurrence of dual-waking wake reaction clinical treatment. [Results] The clinical manifestations of 32 cases of emergence of dual-waking wake-up reaction were different, with different severity and different treatment methods. [Conclusion] The use of cephalosporins, metronidazole, furazolidone and other drugs prone to wake up like reaction, the use of cephalosporins, metronidazole, furazolidone and other drugs during the unfit for consumption of alcoholic foods.