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Ｅｍｔｒｉｃｉｔａｂｉｎｅ(又称 52 4Ｗ 91)是Ａｂｂｏｔｔ公司研制的一种高效ＨＩＶ和ＨＢＶ选择性抑制剂 ,可在体外和体内抑制ＨＩＶ和ＨＢＶ的复制。它为核苷类似物 ,除了含有独特的氧硫杂环烷 ,其最具抗病毒活性的对映体具 1 β Ｌ构型而不是天然核苷所具有的 1 β Ｄ构
Emtricitabine (also known as 52 4W 91) is a highly selective HIV and HBV inhibitor developed by Abbott that inhibits the replication of HIV and HBV in vitro and in vivo. It is a nucleoside analog except that it contains a unique oxathiolane whose most antiviral activity enantiomer has a 1 β L configuration rather than the 1 β D structure of a natural nucleoside