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目的:评价液基细胞学(TCT)制片对宫颈上皮内瘤变(CIN)筛查的准确性。方法:2011年5～12月大兴安岭职业学院附属医院采用TCT制片及传统宫颈细胞涂片法分别对2060例、846例受检者进行(CIN)筛查。细胞诊断采用TBS分级系统。结果:TCT薄片法和传统涂片法对ASCUS以上病变的检出率分别为10.5%、5.2%,2者结果差异有显著性意义(P<0.01)。TCT薄片法与病理诊断的阳性符合率为35.5%,显著高于传统涂片法(20.5%),P<0.05。结论:TCT薄片检出ASCUS以上病变阳性率比传统涂片法效果明显。TCT检测的TBS诊断法与阴道镜下活检、病理检查能提高宫颈癌前病变的准确率。
OBJECTIVE: To evaluate the accuracy of liquid-based cytology (TCT) screening for cervical intraepithelial neoplasia (CIN) screening. Methods: From May to December 2011, 2060 cases and 846 subjects underwent CIN screening by TCT and traditional cervical smear in Daxinganling Vocational College Affiliated Hospital. Cell diagnosis using TBS grading system. Results: The detection rates of TCT and traditional smears on ASCUS were 10.5% and 5.2%, respectively. There was significant difference between the two methods (P <0.01). The positive coincidence rate between TCT and pathological diagnosis was 35.5%, which was significantly higher than that of traditional smear method (20.5%) (P <0.05). Conclusion: The positive rate of the lesions detected by TCT is higher than that of the traditional smear method. TCT test TBS diagnosis and colposcopy biopsy, pathological examination can improve the accuracy of cervical precancerous lesions.