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目的探讨糖尿病患者骨代谢指标的改变。方法对 5 8例 2型糖尿病患者进行血Ca、P、AKP、TRAP和尿DPD、Ca/Cr及BMD的测定。结果糖尿病组的BGP显著低于对照组 (P <0 0 0 1,TRAP和尿DPD、Ca/Cr及BMD显著高于对照组 ,糖尿病组的BMD与DPD和BGP有很好的相关性 (r=- 0 .5 2 1和r=0 .40 2 ,P <0 0 0 1。结论糖尿病组的骨吸收增加 ,骨形成减少。
Objective To investigate the changes of bone metabolism in diabetic patients. Methods Serum Ca, P, AKP, TRAP, urinary DPD, Ca / Cr and BMD were measured in 58 patients with type 2 diabetes mellitus. Results The BGP of diabetic group was significantly lower than that of the control group (P <0.01, TRAP and urine DPD, Ca / Cr and BMD were significantly higher than those of the control group, but BMD of DPD was significantly correlated with DPD and BGP = - 0 .5 2 1 and r = 0 .40 2, P <0 0 0 1. Conclusion Diabetes increased bone resorption and reduced bone formation.