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目的分析影响无创机械通气(NIPPV)治疗慢性阻塞性肺疾病急性加重期(AECOPD)呼吸衰竭疗效的相关因素。方法将112例接受NIPPV治疗的AECOPD并发Ⅱ型呼吸衰竭患者的治疗结果和性别、年龄、体重、神智、面罩漏气等因素做回归分析。结果漏气指数、上机吸气压力、上机前呼吸频率与动脉血气二氧化碳分压(PCO2)下降幅度呈负相关,复治患者二氧化碳分压下降幅度大。年龄,漏气指数与预后负相关,体重及意识评分与预后呈正相关。结论上机吸气压,面罩漏气、上机前的意识水平、呼吸频率、和体重、年龄等因素是NIPPV治疗AECOPD合并呼衰患者疗效的重要影响因素。
Objective To analyze the factors influencing the efficacy of NIPPV in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods A total of 112 AECOPD patients with NIPPV complicated with respiratory failure type Ⅱ were analyzed retrospectively according to the results of gender, age, body weight, divine intelligence and mask leak. Results Air leak index, on machine suction pressure, on the machine before the respiration rate and arterial blood gas carbon dioxide partial pressure (PCO2) decline was negatively correlated, retreatment patients with a large decrease in partial pressure of carbon dioxide. Age, air leak index and negative prognosis, weight and consciousness score and prognosis were positively correlated. Conclusions The factors that affect the efficacy of NIPPV in patients with AECOPD complicated with respiratory failure are the factors such as the upper machine suction pressure, the mask leakage, the level of consciousness before going to the machine, respiratory rate, body weight and age.